Personalized genomics

Your DNA.
Your revolution.

The unique genetic code you carry within holds the answers to questions about your health, your potential, and your longevity — TwistGen decodes them.

TwistGen is a personalized genomics platform that brings lifestyle genetics and clinical genomics together into a single, comprehensive approach to your health. From nutrition and exercise optimization to the prevention of serious disease — it all begins with one DNA sample.

From you, for you
Introduction

The medicine of tomorrow
begins today

We live in an era when personalized medicine is no longer a privilege — it's an option. Your genome is the most accurate map of your body: it reveals predispositions, metabolic specifics, athletic potential, and risks that can be prevented.

TwistGen analyzes hundreds of genetic variants (SNPs) relevant to daily life and clinical health, drawing on scientifically verified, peer-reviewed associations between genes and phenotypic traits.


01 — Principle

Science

Every report is grounded exclusively in scientifically verified genetic associations from peer-reviewed studies. The release of your results does not stop our bioinformatics from improving — if science advances on any of the existing variants, we will notify you in writing.

02 — Principle

Personalization

No generic advice. Every recommendation comes from your unique genetic picture. Your result is unique and yours alone.

03 — Principle

Prevention

Knowledge is power. TwistGen gives you the information physicians use for proactive health management.

Lifestyle Genomics

Live in tune
with your DNA

Discover how your genes define your ideal nutrition, physical activity, and ability to clear toxins — and optimize every aspect of your lifestyle on a biological, not generic, basis.

01

Nutrigenetics

Starter package
€388
  • Nutrigenetics panel

The ideal introduction to personal genomics. Discover how your body responds to macronutrients, vitamins, and minerals — and tailor your diet and supplementation to exactly what your genes support.

03

Nutrigenetics + Fitness + Detox

Premium package
€558
  • Nutrigenetics panel
  • Fitness panel
  • Detox panel

A comprehensive lifestyle analysis. Adding the detox panel gives you a complete picture of your body's ability to eliminate toxins, heavy metals, and oxidative stress.

Panel 01
Nutrigenetics

Food matched to your genome

Nutrigenetics is the branch of science that studies how genetic variants influence the metabolism of nutrients, vitamin absorption, and predispositions toward particular dietary patterns. What works for one person can be wrong for another — the reason lies in the genes.

The TwistGen nutrigenetics panel analyzes the genes that regulate carbohydrate metabolism (including gluten and lactose sensitivity), fat metabolism and the omega-3/omega-6 balance, absorption of key vitamins (B12, D, folate), caffeine metabolism, salt sensitivity, and a tendency toward overeating.

MCM6lactose FTOobesity MTHFRfolate CYP1A2caffeine APOEfats VDRvitamin D TCF7L2glucose
Panel 02
Fitness

Train smart, not just hard

Why do some people achieve outstanding endurance results while others excel in sprint disciplines? Why does muscle build quickly and easily for some and take twice as long for others? The answer is in the genes.

The TwistGen fitness panel reveals your genetic predisposition to muscle fiber type (fast vs. slow), VO₂max capacity and cardiorespiratory efficiency, risk of sports injuries (tendons, ligaments), recovery speed and optimal training frequency, and response to specific kinds of physical activity.

ACTN3fiber type ACEVO₂max COL5A1injuries PPARGC1Aendurance IGF1muscle growth IL6recovery
Panel 03
Detox

How efficiently does your body clean itself?

Every day we are exposed to toxic substances — environmental pollutants, pesticides, processed food, alcohol. The body's ability to eliminate them is not the same for everyone — and the difference is genetic.

The detox panel analyzes both phases of liver detoxification: Phase I (cytochrome P450 enzymes that metabolize foreign substances) and Phase II (conjugation enzymes that enable elimination). We reveal predisposition to heavy-metal accumulation, alcohol and drug metabolism efficiency, susceptibility to oxidative stress, and antioxidant capacity.

CYP1A1pollutants GSTM1glutathione SOD2oxidative stress NAT2acetylation ALDH2alcohol NQO1antioxidants
Specialized package

A panel for the
professional athlete

Designed for athletes who want every possible competitive edge. A combination of nutrigenetics, fitness, and psychogenetics in a single protocol that covers body and mind.

Nutrigenetics

A precise nutritional map for peak performance, energy, and recovery. Diet periodization grounded in your genes.

Fitness

Fiber type, hypertrophy capacity, injury risk, and the optimal structure of your training process — based on your genome.

Mental strength

The genetic basis of motivation, stress tolerance, risk-taking, and mental resilience — decisive factors in elite sport.

Interested in the athlete panel?
Clinical Genomics

Prevention is
the most powerful medicine

TwistGen's clinical genomics panels give physicians and patients a window into genetic predispositions tied to specific organ systems — the foundation for a personalized, preventive approach to medicine before symptoms appear.

I

Allergies

Allergology · Immunogenetics

Genetic predisposition to allergic disease is not random — variants in immune-response genes determine who will develop an allergy to pollen, food, pets, or chemicals.

  • Predisposition to atopy and atopic dermatitis
  • Genetic risk of allergic rhinitis and asthma
  • Food allergies — genetic basis
  • Immune system reactivity (Th1/Th2 balance)
  • Sensitivity to insects and contact allergens
II

Dermatology

Skin disease · Photosensitivity

The skin is a mirror of the genome. Predisposition to psoriasis, eczema, melanocytic change, premature skin aging, and UV sensitivity all have a strong genetic component.

  • Melanoma risk and photosensitivity
  • Genetic basis of psoriasis and eczema
  • Predisposition to acne and seborrhea
  • Skin aging — collagen, elastin, antioxidant defense
  • Sensitivity to contact allergens and chemicals
III

Hormones

Endocrine genetics · Metabolism

The hormonal system is the most sensitive part of the human body. Genetic variants regulate the production, metabolism, and receptor sensitivity of key hormones — from thyroxine to cortisol and estrogen.

  • Thyroid function and predisposition to thyroiditis
  • Estrogen metabolism and risk for women's conditions
  • Insulin resistance and type-2 diabetes
  • Cortisol and the genetics of the stress response
  • Testosterone and androgen metabolism
IV

Neurology

Neurogenetics · Cognitive health

Neurological predispositions can be identified genetically decades before symptoms appear. The TwistGen neurology panel supports early risk recognition and timely action.

  • Genetic markers of Alzheimer's disease (APOE, CLU, PICALM)
  • Predisposition to migraine and chronic pain
  • Risk of Parkinson's disease
  • Neuroinflammation and cognitive decline
  • Neurotransmitter metabolism (serotonin, dopamine)
V

Ophthalmology

Eye disease · Visual health

Genetics plays a key role in the leading causes of blindness. Early detection of predispositions makes preventive measures possible — measures that protect vision over the long term.

  • Age-related macular degeneration (AMD)
  • Glaucoma — genetic risk factors
  • Predisposition to diabetic retinopathy
  • Myopia and predisposition to refractive errors
  • Photosensitivity and UV protection
VI

Nephrology

Kidneys · Blood pressure

The kidneys are filters that genetics programs for life. A genetic profile reveals the risk of chronic kidney disease, kidney stones, and hypertension tied to the renal system.

  • Predisposition to chronic kidney disease
  • Genetic risk of kidney stones (oxalate, urate)
  • Hypertension and the renin-angiotensin system
  • Sensitivity to nephrotoxic substances and drugs
  • IgA nephropathy and glomerulonephritis
VII

Immunology

Autoimmunity · Immunodeficiency

The immune system is a balance between protection and self-aggression. A genetic profile reveals predisposition to autoimmune disease, chronic inflammation, and immunodeficiencies.

  • Predisposition to rheumatoid arthritis
  • Systemic lupus erythematosus (SLE)
  • Inflammatory bowel disease (Crohn's, colitis)
  • Inflammatory cytokines and predisposition to sepsis
  • HLA profile and autoimmune risk
VIII

Cardiology

Cardiovascular health · Prevention

Cardiovascular disease remains the leading cause of death. Genomics enables identification of high-risk individuals before the first symptom — and saves lives through timely intervention.

  • Genetic risk of myocardial infarction
  • Predisposition to hypertension and atherosclerosis
  • Inherited cardiomyopathies and arrhythmias
  • Lipid metabolism — LDL, HDL, triglycerides
  • Thrombosis and the genetics of coagulation (Factor V Leiden)
IX

Dentistry

Oral health · Genomics

Oral health is closely tied to overall health, and genetics determines predisposition to periodontal disease, dental caries, and inflammatory changes in the oral cavity.

  • Predisposition to periodontitis and gingivitis
  • Genetic susceptibility to caries (salivary traits)
  • Oral autoimmune manifestations (lichen planus)
  • Calcium metabolism and bone density (implants)
  • Inflammatory response to oral bacteria
The science behind us

The science behind
every report

TwistGen reports are grounded exclusively in globally recognized peer-reviewed studies. We don't use AI-based models until they have been scientifically validated. In other words: every genetic association has its own study.

500+ SNP variants
9 Clinical specialties
4 Lifestyle panels
ISO Certified lab
Process

Four steps to
your genome

01

Order online

Choose the panel that matches your needs and order directly through our site. The collection kit is delivered to your home address.

02

Saliva sample

Sampling is simple and painless — cheek swabs or saliva. Send the sample back in the secure return envelope provided.

03

Laboratory analysis

Your sample is analyzed by an ISO-certified laboratory at a University Center in Germany, using the latest chip-based or NGS genotyping platforms.

04

Your report

Within 5–6 weeks you receive a detailed, easy-to-read report with concrete recommendations. A specialist medical team is on hand to answer any questions and refer you for further consultations as needed.

Frequently asked

What is personalized genomics, and why does it matter?

Personalized genomics is the field of medicine that uses information from your genetic code to deliver tailored health recommendations. Unlike standard laboratory tests, which measure the body's current state, genetic tests reveal permanent predispositions encoded in your DNA — and remain valid throughout your life.

In Serbia and the wider Southeast European region, TwistGen is a pioneer of accessible, scientifically grounded genomics — available not only to clinics but to individual users who want to take an active role in managing their own health.

What is nutrigenetics?

Nutrigenetics (or nutrigenomics) is the science of the interaction between genes and nutrients. It studies how genetic variants influence the way our bodies metabolize food, absorb vitamins, and respond to different dietary patterns. A nutrigenetic test can reveal, for example, whether you have a genetic predisposition to lactose intolerance, how your body metabolizes caffeine, what your optimal macronutrient balance looks like, or which vitamin deficiencies may be genetically driven.

Genetic testing for sport and fitness

Fitness genomics is one of the fastest-growing segments of applied genetics. Based on genes such as ACTN3 (muscle fiber type), ACE (cardiovascular efficiency), and COL5A1 (tendon-injury risk), it's possible to design a personalized training plan that is biologically compatible with your genome. That means better results, faster recovery, and a lower probability of injury.

Genetic testing and disease prevention

TwistGen's clinical genomics panels are not diagnostic tests — they are instruments of prevention. By identifying genetic predispositions to cardiovascular disease, diabetes, neurodegenerative conditions, or autoimmune disorders, physicians and patients gain valuable information for designing preventive protocols, more frequent screening, targeted supplementation, and lifestyle changes that have a real genetic basis.

Where to provide a sample for the TwistGen test

TwistGen partners with a network of laboratories, and you can also order a genetic test online with the collection kit delivered directly to your address. Sampling can be done in a partner lab or at home, and laboratory analysis is performed at an ISO-certified lab at a University Center in Germany. Results are delivered electronically as a detailed, expert report with concrete recommendations.

Start today

Your genome is waiting
to be read

Order a TwistGen test, and in just over a month you'll receive a report that can change your life — how you eat, live, and train, and how you take care of your health.

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